2-9 Reviews of fair comparisons should be systematic

Reviews that do not use systematic methods may result in biased or imprecise estimates of the effects of treatments because the selection of studies for inclusion may be biased or the methods may result in some studies not being found. In addition, the appraisal of some studies may be biased, or the synthesis of the results of the selected studies may be inadequate or inappropriate.

Whenever possible, use systematic reviews of fair comparisons rather than non-systematic reviews of fair comparisons of treatments to inform your decisions.

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A University of Massachusetts Medical School text on biases.

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Sunn Skepsis

Denne portalen er ment å gi deg som pasient råd om kvalitetskriterier for helseinformasjon og tilgang til forskningsbasert informasjon.

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Dodgy academic PR

Ben Goldacre: 58% of all press releases by academic institutions lacked relevant cautions and caveats about the methods and results reported

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The Systematic Review

This blog explains what a systematic review is, the steps involved in carrying one out, and how the review should be structured.

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Cartoon and blog about how poorly performed systematic reviews and meta-analyses may misrepresent the truth.

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Book cover


Another example of unnecessary research, yet again because the results of preceding studies had not been gathered together and analyzed, […]

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Book cover

Is one study ever enough?

The simple answer is ‘hardly ever’. Very seldom will one fair treatment comparison yield sufficiently reliable evidence on which to […]

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